James Zacny, Ph.D.

Professor Emeritus of Anesthesia & Critical Care

Training

B.S. - 1973 - 1978
St. Joseph College - Rennselaer IN, USA - Psychology

Ph.D. - 1978 - 1983
West Virginia University - Morgantown WV, USA - Psychology

Fellowship - 1983 - 1986
The Johns Hopkins University School of Medicine - Baltimore, Maryland USA - Psychopharmacology

Clinical Interests

Determining risk factors in chronic pain patients for prescription opioid misuse

Academic Interests

Abuse liability of prescription opioids and other CNS agents; drug-alcohol interactions; studying th

Recent Publications

Zacny JP: What do we know (and not know) about prescription opioid misuse in the context of pain management? Pain Manage 1:395-398, 2011. Zacny JP, Paice JA, Coalson DW: Subjective and psychomotor effects of carisoprodol in combination with oxycodone in healthy volunteers. Drug Alcohol Depend, in press, 2011. Doi:10.1016/j.drugalcdep.2011.07.006.

Zacny JP, Paice JA, Coalson DW: Characterizing the subjective and psychomotor effects of carisoprodol in healthy volunteers. Pharmacol Biochem Behav 100:138-143, 2011.

Zacny JP, Gutierrez, S: Subjective, psychomotor, and physiological effects of oxycodone alone and in combination with ethanol in healthy volunteers. Psychopharmacology epub ahead of print (PMID:21603891), 2011

Zacny JP, Gutierrez S, Kirulis K, McCracken SG: Psychopharmacological effects of oxycodone in volunteers with and without generalized anxiety disorder. Exp Clin Psychopharmacol 19:85-94, 2011

Niesters M, Dahan A, Kest B, Zacny J, Stijnen T, Aarts L, Sarton E: Do sex differences exist in opioid analgesia? A systematic review and meta-analysis of human experimental and clinical studies. Pain 151:61-68, 2010

Zacny JP, Jun JM: Lack of sex differences to the subjective effects of nitrous oxide in healthy volunteers. Drug Alcohol Depend 112:251-254, 2010

Zacny JP, Drum M: Psychopharmacological effects of oxycodone in healthy volunteers: roles of alcohol-drinking status and sex. Drug Alcohol Depend 107:209-214, 2010

Zacny JP: A possible link between sensation-seeking status and positive subjective effects of oxycodone in healthy volunteers. Pharmacol Biochem Behav 95:113-120, 2010

Zacny JP, de Wit H: The prescription opioid, oxycodone, does not alter behavioral measures of impulsivity in healthy volunteers. Pharmacol Biochem Behav 94:108-113, 2009

Zacny JP, Gutierrez S: Within-subject comparison of the psychopharmacological profiles of oral hydrocodone and oxycodone combination products in non-drug-abusing volunteers. Drug Alcohol Depend 101:107-113, 2009

Zacny JP, Walker DJ, Derus LM: Choice of nitrous oxide and its subjective effects in light and moderate drinkers. Drug Alcohol Depend 98:163-168, 2008

Zacny JP, Lichtor SA: Nonmedical use of prescription opioids: Motive and ubiquity issues. J Pain 9:473-486, 2008

Zacny JP, Lichtor SA: Reply to the Commentaries. J Pain 9:494- 496, 2008

Zacny JP, Gutierrez S: Subjective, psychomotor, and physiological effects profile of hydrocodone/acetaminophen and oxycodone/acetaminophen combination products. Pain Med 9:433- 443, 2008

Comer SD, Ashworth JB, Foltin RW, Johanson CE, Zacny JP, Walsh SL: The role of human drug self-administration procedures in the development of medications. Drug Alcohol Depend 96:1-15, 2008

Zacny JP, Walker DJ, Drum M, Sells M: Choice of sevoflurane and its subjective and psychomotor effects in light and moderate drinkers. Drug Alcohol Depend 94:101-108, 2008

Zacny JP, Lichtor SA: Within-subject comparison of the psychopharmacological profiles of oral oxycodone and oral morphine in non-drug-abusing volunteers. Psychopharmacology 196:105-117, 2008

Zacny JP: Chronic pain and driving: Proceed with caution. Pain 122:6-7, 2006

Beckman NJ, Zacny JP, Walker DJ: Within-subject comparison of the subjective and psychomotor effects of a gaseous anesthetic and two volatile anesthetics in healthy volunteers. Drug Alcohol Depend 81:89-95, 2006

Zacny JP: Profiling the subjective, psychomotor, and physiological effects of tramadol in recreational drug users. Drug Alcohol Depend 80:273-278, 2005

Zacny JP, Gutierrez S, Bolbolan SA: Profiling the subjective, psychomotor, and physiological effects of a hydrocodone/acetaminophen product in recreational drug users. Drug Alcohol Depend 78:243-252, 2005

Walker DJ, Beckman NJ, Zacny JP: Reinforcing and subjective effects of the volatile anesthetic, sevoflurane. Drug Alcohol Depend 76:191-201, 2004

Zacny JP, Beckman NJ: The effects of a cold water stimulus on butorphanol effects in males and females. Pharmacol Biochem Behav 78:653-659, 2004

Gutierrez S, Ang-Lee MK, Walker DJ, Zacny JP: Assessing subjective and psychomotor effects of the herbal medication valerian in healthy volunteers. Pharmacol Biochem Behav 78:57- 64, 2004

Zacny JP, Goldman RE: Characterizing the subjective, psychomotor, and physiological effects of oral propoxyphene in non-drug-abusers. Drug Alcohol Depend 73:133-140, 2004

Zacny JP, Gutierrez S: Characterizing the subjective, psychomotor, and physiological effects of oral oxycodone in non- drug-abusing volunteers. Psychopharmacology 170:242-254, 2003

Expert Panel (including Zacny JP): Abuse liability assessment of CNS drugs: conclusions, recommendations, and research priorities. Drug Alcohol Depend 70:S107-S114, 2003

Zacny J, Bigelow G, Compton P, Foley K, Iguchi M, Sannerud C: College on Problems of Drug Dependence Taskforce on Prescription Opioid Non-Medical Use and Abuse: Position Statement. Drug Alcohol Depend 69:215-232, 2003

Walker DJ, Zacny JP: Bitonic dose-response functions for reinforcing and self-reported effects of nitrous oxide in humans. Pharmacol Biochem Behav 74:851-857, 2003

Zacny JP: Characterizing the subjective, psychomotor, and physiological effects of a hydrocodone combination product (Hycodan®) in non-drug-abusing volunteers. Psychopharmacology 165:146-156, 2003

Walker DJ, Zacny JP: Analysis of the reinforcing and subjective effects of different doses of nitrous oxide using a free-choice procedure. Drug Alcohol Depend 66:93-103, 2002

Zacny JP, Hurst RJ, Graham L, Janiszewski DJ: Pre-operative dental anxiety and mood changes during nitrous oxide inhalation. J Am Dent Assoc 133:82-88, 2002

Walker DJ, Zacny JP: Lack of effects of ethanol pretreatment on the abuse liability of nitrous oxide in light and moderate drinkers. Addiction 96:1839-1845, 2001

Walker DJ, Zacny JP, Galva KE, Lichtor JL: Subjective, psychomotor, and physiological effects of cumulative doses of mixed-action agonists in healthy volunteers. Psychopharmacology 155: 362-371, 2001

Walker DJ, Zacny JP: Within- and between-subject variability in the reinforcing and subjective effects of nitrous oxide in healthy volunteers. Drug Alcohol Depend 64:85-96, 2001

Zacny JP: Effects of sex on morphine responses in humans: a retrospective analysis. Drug Alcohol Depend 63:23-28, 2001

Draganich LF, Zacny JP, Klafta J, Karrison T: The effects of antidepressants on obstructed and unobstructed gait in the healthy elderly. J Gerentol A Biol Sci Med Sci 56:M36-M41, 2001

Hill JL, Zacny JP: Comparing the subjective, psychomotor, and physiological effects of intravenous hydromorphone and morphine in normal volunteers. Psychopharmacology 152:31-39, 2000

Zacny JP, Conran A, Pardo H, Coalson DW, Black M, Klock PA, Klafta JM: Effects of naloxone on nitrous oxide actions in healthy volunteers. Pain 83:411-418, 2000

Zacny J P, Janiszewski D, Sadegi P, Black ML: Reinforcing and other behavioral effects of sevoflurane and nitrous oxide in moderate-drinking healthy volunteers. Addiction 94:1817-1828, 1999

Sadeghi P, Zacny JP: Anesthesia is a risk factor for drug and alcohol craving and relapse in ex-abusers: a hypothesis. Med Hypotheses 53:490-496, 1999

Janiszewski DJ, Galinkin JL, Klock PA, Coalson DW, Pardo H, Zacny JP: The effects of sub anesthetic concentrations of sevoflurane and nitrous oxide, alone and in combination, on analgesia, mood, and psychomotor performance in healthy volunteers. Anesth Analg 88:1149-1154, 1999

Walker DJ, Zacny JP: Subjective, psychomotor, and physiological effects of cumulative doses of opioid mu agonists in healthy volunteers. J Pharmacol Exp There 289:1454-1464, 1999

Black ML, Hill JL, Zacny JP: Behavioral and physiological effects of remifentanil and alfentanil in healthy volunteers. Anesthesiology 90:718-726, 1999

Zacny JP, Galinkin JL: Psychotropic drugs used in anesthesia practice: abuse liability and epidemiology of abuse. Anesthesiology 90:269-288, 1999

Zacny JP, Hill JL, Black ML, Sadeghi P: Comparing the subjective, psychomotor, and physiological effects of intravenous pentazocine and morphine in healthy volunteers. J of Pharmacol Exp There 286:1197-1207, 1998

Walker DJ, Zacny JP: Subjective, psychomotor, and analgesic effects of oral codeine and morphine in healthy volunteers. Psychopharmacology 140:191-201, 1998

Zacny JP, Camarillo VM, Sadeghi P, Black M: Effects of ethanol and nitrous oxide, alone and in combination, on mood, psychomotor performance and pain reports in healthy volunteers. Drug Alcohol Depend 52:115-123, 1998

Mitchell SM, de Wit H, Zacny JP: The impact of three economic factors on cigarette consumption. Hum Psychopharmacol 13:259- 266, 1998

Galinkin JL, Janiszewski D, Young CJ, Klafta JM, Klock PA, Coalson DW, Apfelbaum JL, Zacny JP: The subjective, psychomotor, cognitive and analgesic effects of sub anesthetic concentrations of sevoflurane and nitrous oxide. Anesthesiology 87:1082-1088, 1997

Zacny JP, Cho AM, Toledano AY, Galinkin J, Coalson DW, Klock PA, Klafta J M, Young CJ: Effects of information on the reinforcing, subjective, and psychomotor effects of nitrous oxide in healthy volunteers. Drug and Alcohol Depend 48:85-95, 1997

Zacny JP, Conley K, Galinkin J: Comparing the subjective, psychomotor, and physiological effects of buprenorphine and morphine in healthy volunteers. J Pharmacol Exp There 282:1187- 1197, 1997

Young CJ, Coalson DW, Klock A, Klafta J, Goldsher G, Apfelbaum JL, Zacny JP: Analgesic and other effects of thiopental at steady-state concentrations in human volunteers. Acta Anaesthesiol Scand 41:903-910, 1997

Hasegawa AE, Zacny JP: Effects of three L-type calcium channel blockers on morphine effects in healthy volunteers. Anesth Analg 85:633-638, 1997

Conley KM, Toledano AY, Apfelbaum JL, Zacny JP: The modulating effects of a cold water stimulus on opioid effects in volunteers. Psychopharmacology 131: 313-320, 1997

Zacny JP, Conley K, Marks S: Comparing the subjective, psychomotor, and physiological effects of intravenous nalbuphine and morphine in healthy volunteers. J Pharmacol Exp There 280:1159-1169, 1997

Zacny JP, Mitchell SM, de Wit H: The effects of ethanol on the relative preference for cigarettes. Behav Pharmacol 7:75-81, 1997

Cho AM, Toledano AY, Apfelbaum JL, Zacny JP. The effects of alcohol history on the reinforcing, subjective and psychomotor effects of nitrous oxide in healthy volunteers. Drug Alcohol Depend 45:63-70,1997

Zacny JP: Should people taking opioids for medical reasons be allowed to work and drive? (Invited editorial). Addiction 91:1581-1584, 1996

Zacny JP, Klafta JM, Coalson DW, Marks S, Young CJ, Klock PA, Toledano A Y, Jordan N, Apfelbaum J L: The reinforcing effects of brief exposures to nitrous oxide in healthy volunteers. Drug Alcohol Depend 42:197-200, 1996

Zacny JP, Coalson DW, Klafta JM, Klock PA, Alessi R, Rupani G, Young CJ, Patil PG, Apfelbaum JL: Midazolam does not influence intravenous fentanyl-induced analgesia in healthy volunteers. Pharmacol Biochem Behav 55:275-280, 1996

Zacny JP, McKay MA, Toledano AY, Marks S, Young CJ, Klock PA, Apfelbaum JL: The effects of a cold-water immersion stressor on the reinforcing and subjective effects of fentanyl in healthy volunteers. Drug Alcohol Depend 42:133-142, 1996

Zacny JP, Coalson DW, Young CJ, Klafta J, Lichtor JL, Rupani G, Thapar P, Apfelbaum JL: The effects of sub-hypnotic doses of proposal on cold pressor-induced pain in healthy volunteers. J Clin Anesth 8:469-474, 1996

Zacny JP, Cho AM, Coalson DW, Rupani G, Young CJ, Klafta JL, Klock PA, Apfelbaum JL: Differential acute tolerance development to effects of nitrous oxide in humans. Neurosci Lett, 209:73-76, 1996

Yajnik S, Zacny JP, Young CJ, Lichtor JL, Rupani G, Klafta JM, Coalson DW, Apfelbaum JL: Lack of acute tolerance development to the subjective, cognitive, and psychomotor effects of nitrous oxide in healthy volunteers. Pharmacol Biochem Behav 54:501- 508, 1996

Zacny JP, Lichtor JL, Coalson DW, Alessi R, Goldsher G, Young CJ, Apfelbaum JL, Conley KM: Examining the subjective, psychomotor-impairing, and reinforcing effects of nitrous oxide in healthy volunteers: a dose-response analysis. Behav Pharmacol 7:194-199, 1996

Zacny JP, Lichtor JL, Klafta JM, Alessi R, Apfelbaum JL: The effects of transnasal butorphanol on mood and psychomotor functioning in healthy volunteers. Anesth Analg 82:931-935, 1996

Zacny JP, Yajnik S, Lichtor JL, Klafta JM, Young CJ, Thapar P, Rupani G, Coalson DW, Apfelbaum JL: The acute and residual effects of sub anesthetic concentrations of isoflurane/nitrous oxide combinations on cognitive and psychomotor performance in healthy volunteers. Anesth Analg 82:153-157, 1996

Zacny JP: A review of the effects of opiates on psychomotor and cognitive functioning in humans. Exp Clin Psychopharmacol 3:432-466, 1995

de Wit H, Zacny JP: The abuse potential of nicotine replacement therapies. CNS Drugs 4:456-468, 1995

Patil PG, Apfelbaum JL, Zacny JP: The effects of a cold-water stressor on psychomotor and cognitive functioning in humans. Physio Behav 58:1281-1286, 1995

Klafta JM, Zacny JP, Young CJ: Neurological and psychiatric adverse effects of anesthetics: Epidemiology and treatment. Drug Saf 13:281-295, 1995

Zacny JP, Yajnik S, Coalson D, Lichtor JL, Thapar P, Apfelbaum JL, Rupani G, Young C, Klafta J: Flumazenil may attenuate some subjective effects of nitrous oxide in humans: a preliminary report. Pharmacol Biochem Behav 51:815-819, 1995

Mitchell SH, de Wit H, Zacny JP: Effects of varying ethanol dose on cigarette consumption in healthy volunteers. Behavioural Pharmacol 6:359-365, 1995

Pirec V, Coalson DW, Lichtor JL, Klafta J, Young C, Rupani G, Apfelbaum JL, Zacny JP: Cold water immersion modulates the reinforcing effects of nitrous oxide in healthy volunteers. Exp Clin Psychopharmacol 3: 148-155, 1995

Mitchell SH, de Wit H, Zacny JP: Caffeine withdrawal symptoms and self-administration following caffeine abstinence. Pharmacol Biochem Behav 51:941-945, 1995

Pirec V, Patterson T, Thapar P, Apfelbaum JL, Zacny JP: Effects of sub anesthetic concentrations of nitrous oxide on cold-pressor pain in humans. Pharmacol Biochem Behav 51:323-329, 1995

Zacny JP, Coalson D, Young C, Klafta J, Rupani G, Thapar P, Choi M, Apfelbaum JL: A dose-response study of the effects of intravenous midazolam on cold pressor-induced pain. Anesth Analg 80:521-525, 1995

Thapar P, Zacny JP, Choi M, Apfelbaum JL: Objective and subjective impairment from often-used sedative combinations in ambulatory surgery, using alcohol as a benchmark. Anesth Analg 80:1092-1098, 1995

Mitchell SH, Laurent CL, de Wit H, Zacny JP: Effects of price, "openness" of the economy and magnitude of the alternative non-drug reinforcer on responding for caffeinated coffee. Hum Psychopharmacol 10:39-46, 1995

Thapar P, Zacny JP, Thompson W, Apfelbaum JL: Using alcohol as a metric to compare recovery profiles of often-used sedative agents in ambulatory surgery. Anesthesiology 82:53-59, 1995

Yajnik S, Thapar P, Lichtor JL, Patterson T, Zacny JP: Effects of marijuana history on the subjective, psychomotor, and reinforcing effects of nitrous oxide in humans. Drug Alcohol Depend 36:227-236, 1994

Zacny JP, Coalson DW, Lichtor JL, Yajnik S, Thapar P: Effects of naloxone on the subjective and psychomotor effects of nitrous oxide in humans. Pharmacol Biochem Behav 49:573-578, 1994

Zacny JP, Lichtor JL, Thapar P, Coalson DW, Flemming D, Thompson W: Comparing the subjective, psychomotor, and physiological effects of intravenous butorphanol and morphine in healthy volunteers. J Pharmacol Exp There 270:579-588, 1994

Zacny JP, Lichtor JL, Coalson DW, Flemming D, Apfelbaum JL, Foster V: Time course of effects of brief inhalations of nitrous oxide in normal volunteers. Addiction 89:831-840, 1994

Doty P, Zacny JP, de Wit H: Effects of ondansetron pretreatment on acute responses to ethanol in social drinkers. Behav Pharmacol 5:461-469, 1994

Mitchell SH, de Wit H, Zacny JP: Effects of varying the "openness" of an economy on responding for tobacco cigarettes. Behav Pharmacol 5:159-166, 1994

Zacny JP, Sparacino G, Hoffman PM, Martin R, Lichtor JL: The subjective, behavioral and cognitive effects of sub anesthetic concentrations of isoflurane and nitrous oxide in healthy volunteers. Psychopharmacology 114:409-416, 1994

Zacny JP, Lichtor JL, Flemming D, Coalson DW, Thompson WK: A dose-response analysis of the subjective, psychomotor, and physiological effects of intravenous morphine in healthy volunteers. J Pharmacol Exp There 268:1-9, 1994

Zacny JP, Yajnik S: Effects of calcium channel inhibitors on ethanol effects and pharmacokinetics in healthy volunteers. Alcohol 10:505-509, 1993

Dohrn CS, Lichtor JL, Coalson DW, Flemming D, Zacny JP: Reinforcing effects of extended inhalation of a low nitrous oxide concentration in humans. Pharmacol Biochem Behav 46:927- 932, 1993

Wang W, Cone EJ, Zacny JP: Immunoassay evidence for fentanyl in hair of surgery patients. Forensic Sci Int 61:65-72, 1993

Zacny JP, Lichtor JL, Thompson W, Apfelbaum JL: Propofol at a sub anesthetic dose may have abuse potential in healthy volunteers. Anesth Analg 77:544-552, 1993

Dohrn CS, Lichtor JL, Coalson DW, Flemming D, Zacny JP: Subjective and psychomotor effects of bolus doses of nitrous oxide in humans. Hum Psychopharmacol 8:97-106, 1993

Zacny JP, Lichtor JL, Binstock W, Coalson DW, Cutter T, Flemming DC, Glosten B: Subjective, behavioral and physiological responses to intravenous meperidine in healthy volunteers. Psychopharmacology 111:306-314, 1993

Lichtor JL, Zacny JP, Coalson DW, Flemming DC, Uitvlugt A, Apfelbaum JL, Lane BS, Thisted RA: The interaction between alcohol and the residual effects of thiopental anesthes

ia. Anesthesiology 79:28-35, 1993

Zacny JP, Lichtor JL, Zaragoza JG, Coalson DW, Uitvlugt AM, Flemming DC, Binstock WB, Cutter T, Apfelbaum J: Assessing the behavioral effects and abuse potential of proposal bolus injections in healthy volunteers. Drug Alcohol Depend 32:45-57, 1993

Zacny JP, Apfelbaum J, Lichtor JL, Zaragoza JG: Effects of a 5- HT3 antagonist, ondansetron, on cigarette smoking, smoke exposure, and mood in cigarette smokers. Pharmacol Biochem Behav 44:387-391, 1993

Dohrn CS, Lichtor JL, Coalson DW, Uitvlugt A, deWit H, Zacny JP: Reinforcing effects of extended inhalation of nitrous oxide in humans. Drug Alcohol Depend 31:265-280, 1993

Zacny JP, Lichtor JL, Zaragoza JG, de Wit H: Effects of fasting on responses to intravenous fentanyl in healthy volunteers. J Subst Abuse 4:197-207, 1992

Zacny JP, Divane WT, de Wit H: Assessment of magnitude and availability of a non-drug reinforcer on preference for a drug reinforcer. Hum Psychopharmacol 7:281-286, 1992

Zacny JP, Lichtor JL, Zaragoza JG, de Wit H: Subjective and behavioral responses to intravenous fentanyl in healthy volunteers. Psychopharmacology 107:319-326, 1992

Zacny JP, Lichtor JL, Coalson DW, Finn RS, Uitvlugt AM, Glosten B, Flemming DC, Apfelbaum JL: Subjective, behavioral and physiological responses to subanesthetic doses of propofol in healthy volunteers. Anesthesiology 76:696-702, 1992

Chait LD, Zacny JP: Reinforcing and subjective effects of oral delta-9-THC and smoked marijuana in humans. Psychopharmacology 107:255-262, 1992

Zacny JP, Lichtor JL, de Wit H: Subjective, behavioral, and physiologic responses to intravenous dezocine in healthy volunteers. Anesth Analg 74:523-530, 1992

Zacny JP, Bodkar BK, de Wit H: Effects of setting on the subjective and behavioral effects of d-amphetamine in humans. Addict Behav 17:27-33, 1992

Zacny JP, de Wit H: The effects of a restricted feeding regimen on cigarette smoking in humans. Addict Behav 17:149-157, 1992

Dohrn CS, Lichtor JL, Finn RS, Coalson DW, Uitvlugt A, de Wit H, Zacny JP: Subjective and psychomotor effects of nitrous oxide in normal volunteers. Behav Pharmacol 3:19-30, 1992

Lichtor JL, Zacny JP, Apfelbaum J, Rupani G, Thisted R, Dohrn C, Kortilla K: Alcohol after intravenous midazolam-fentanyl sedation: Effects on psychomotor functioning. Br J Anaesth 67:579-584, 1991

Evans SM, Zacny JP, Woolverton WL, Johanson CE: The discriminative stimulus properties of histamine H1-antagonists in pigeons. Behavl Pharmacol 2:447-460, 1991

Zacny JP, de Wit H: Effects of food deprivation on self- administration and subjective effects of marijuana in humans. Psychol Rep 68:1263-1274, 1991

Zacny JP, Chait LD: Response to marijuana as a function of potency and breathhold duration. Psychopharmacology 103:223- 226, 1991

Lichtor JL, Zacny JP, Kortilla K, Apfelbaum JL, Lane BS, Rupani G, Thisted RA, Dohrn C: Alcohol after midazolam sedation: Does it really matter? Anesth Analg 72:661-666, 1991

Zacny JP: Discriminative stimulus effects of H1-antihistamines in cocaine-trained pigeons. Behav Pharmacol 1:261-265, 1990

Zacny JP, de Wit H: Effects of food deprivation on cigarette consumption in humans. Br J Addict 85:555-560, 1990

Evans S, Zacny JP, Johanson J: A three-choice discrimination between amphetamine, fenfluramine and saline. Pharmacol Biochem Behav 35:971-980, 1990

Zacny JP, Virus RM, Kleven MS, Woolverton WL: Tolerance and cross-tolerance to 3,4-Methylenedioxymethamphetamine (MDMA), methamphetamine and methylenedioxyamphetamine. Pharmacol Biochem Behav 35:637-642, 1990

Zacny JP, de Wit H: Effects of food deprivation on responses to marijuana in humans. Behav Pharmacol 1:177-185, 1989

Zacny JP, de Wit H: Effects of food deprivation on subjective responses to d-amphetamine in humans. Pharmacol Biochem Behav 34:791-795, 1989

Zacny JP, Woolverton WL: Discriminative stimulus properties of local anesthetics in d-amphetamine- and pentobarbital-trained pigeons. Pharmacol Biochem Behav 33:527-531, 1989

Zacny JP, Chait LD: Breathhold duration and response to marijuana smoke. Pharmacol Biochem Behav 33:481-484, 1989

Zacny JP, Stitzer ML: Cigarette brand-switching: Effects on smoke exposure and smoking behavior. J Pharmacol Exp There 246:619-627, 1988

Zacny JP, Stitzer ML, Brown FJ, Yingling JE, Griffiths RR: Human cigarette smoking: Effects of puff and inhalation parameters on smoke exposure. J Pharmacol Exp There 240:554-564, 1987

Zacny JP, Stitzer ML, Yingling JE: Cigarette filter vent blocking: Effects on smoking topography and carbon monoxide exposure. Pharmacol Biochem Behav 25:1245-1252, 1987

Zacny JP, Stitzer ML: Effects of puff size instruction on puff volume. Addict Behav 11:17-23, 1986

Zacny JP, Stitzer ML: Effects of smoke deprivation interval on puff topography. Clin Pharmacol Ther 38:109-115, 1985

Goodman I, Zacny JP, Osman A, Azzaro A, Donovan C: Dopaminergic nature of feeding-induced behavioral stereotypes in stressed pigeons. Pharmacol Biochem Behav 18:153-158, 1983

Goodman I, Zacny JP, Osman A, Azzaro A, Donovan C: Lesion- produced telencephalic catecholamine imbalances and altered operant pecking rate in pigeons. Physiol Behav 29:1045-1050, 1982

Palya WL, Zacny JP: Stereotyped adjunctive pecking by caged pigeons. Anim Learn Behav 6:293-303, 1980