Department Research

Aspiring clinician-scientists are encouraged to complete 6-18 months of research in addition to six months of clinical training. Research opportunities are available in a variety of areas, either working in concert with a faculty member on an ongoing project or undertaking a new investigation. The research interests of some of the current faculty are described below.

Residents may undertake the accompanying clinical training at the beginning or end of the research training period, and may choose from a number of options available to those electing one of the clinical tracks. The Department is proud of its contributions to academic research; such rotations supplement sound clinical rotations, as we believe that a sound clinical foundation is essential to both the academic and private practice of anesthesia.

The Department of Anesthesia and Critical Care offers a joint Anesthesiology/Clinical Pharmacology Training Program (ACPTP). The goal of this program is to provide superior training in clinical anesthesiology and to extend this training to include an in-depth knowledge of the principles, practice and research methods of clinical pharmacology.

The latter is integrated throughout the clinical anesthesia training period and in an additional fellowship year. The successful candidate will be eligible to sit for the examinations of the American Board of Anesthesiology and the American Board of Clinical Pharmacology at the conclusion of training.

The program consists of a continuum, adding additional didactic training in clinical pharmacology during the CA-1 and CA-2 years.

The second two years of training consist of a combined program designed to meet the requirements of the American Board of Clinical Pharmacology.

At least six months of this period will be clinical as described by the American Board of Anesthesiology, but this time may be used in conjunction with ongoing work in clinical pharmacology. The candidate, under the direction of a mentor, will design and complete a research program focused on the principles of clinical pharmacology as they apply to the practice of anesthesia and critical care.

Faculty Research Interests

Further information about our faculty may be found in the Faculty Pages themselves and on the Department Grants List page.

Participation by residents is welcomed in these and other investigations.

Dr. Allan Klock studies electronic database information systems to help physicians transfer information, increase the role of anesthesiologists in improving the choices and outcomes of care, implement guidelines, do preoperative assessments and care for patients more efficiently.

Dr. Avery Tung studies the effects of sedation and anesthesia on restorative sleep.

Dr. Mark Chaney is studying the efficacy of transesophageal echocardiography and stress reduction in various clinical situations, including regional and organ blood flow.

Research into the gender differences of anesthetics is conducted by Drs. Dennis Coalson.

A pain management program is operated by Drs. Magdalena Anitescu and Tariq Malik. Dr. Magdalena Anitescu studies the efficiency of traditional and newly emergent discography techniques (functional anesthetic discogram) to identify pain generators in low back pain.

Drs. Dan McGehee, Ming Xu, and Jimmy Xie study the pharmacology and biophysics of anesthetics.

Clinical investigations into recovery from anesthesia, particularly with respect to patients undergoing surgery as outpatients who suffer from perioperative anxiety, are underway by Drs. Jeff Apfelbaum, Allan Klock, Wendy Binstock, and Dennis Coalson.

Studies of histaminergic, enteric, and autonomic pharmacology are in process under the aegis of Drs. Jonathan Moss and Chun Su Yuan.

Pharmacological studies of intensive care patients are undertaken by Drs. Mike O'Connor and Avery Tung.

Studies of patient safety are performed by Drs. Michael O'Connor, Allan Klock, and Steve Small.

Drs. Jon Moss and Chun-Su Yuan helped develop quaternary naltrexone compounds to reverse the peripheral effects of narcotics and are now studying their applicability in other clinical situations.

Our airway laboratory is run by Drs. Jerry Klafta and Allan Klock.