Dr. Nagele is an internationally recognized trauma anesthesiologist, researcher and educator. An authority on perioperative outcomes research, he focuses on to better predict, diagnose, prevent, and treat major cardiac events in surgical patients. He discovered that novel heart biomarkers may predict heart attacks in patients undergoing non-cardiac surgery.
He has also conducted ground-breaking work suggesting that a brief inhalation of nitrous oxide, commonly known as laughing gas, improves severe symptoms of depression and suicidal thoughts.
Trends and In-Hospital Mortality for Perioperative Myocardial Infarction After the Introduction of a Diagnostic Code for Type 2 Myocardial Infarction in the United States Between 2016 and 2018.
Trends and In-Hospital Mortality for Perioperative Myocardial Infarction After the Introduction of a Diagnostic Code for Type 2 Myocardial Infarction in the United States Between 2016 and 2018. Anesth Analg. 2023 Feb 16.
PMID: 36795598
Preoperative ?-Blocker Therapy and Stroke or Major Adverse Cardiac Events in Major Abdominal Surgery: A Retrospective Cohort Study.
Preoperative ?-Blocker Therapy and Stroke or Major Adverse Cardiac Events in Major Abdominal Surgery: A Retrospective Cohort Study. Anesthesiology. 2023 01 01; 138(1):42-54.
PMID: 36227278
Nitrous Oxide, a Rapid Antidepressant, Has Ketamine-like Effects on Excitatory Transmission in the Adult Hippocampus.
Nitrous Oxide, a Rapid Antidepressant, Has Ketamine-like Effects on Excitatory Transmission in the Adult Hippocampus. Biol Psychiatry. 2022 12 15; 92(12):964-972.
PMID: 36050137
Preoperative Assessment of Anxiety and Depression Using Computerized Adaptive Screening Tools: A Pilot Prospective Cohort Study.
Preoperative Assessment of Anxiety and Depression Using Computerized Adaptive Screening Tools: A Pilot Prospective Cohort Study. Anesth Analg. 2022 04 01; 134(4):853-857.
PMID: 34958316
The Importance of Definitive Trials: The VIXIE Trial.
The Importance of Definitive Trials: The VIXIE Trial. Anesthesiology. 2022 03 01; 136(3):403-404.
PMID: 35120197
Normalized Subendocardial Myocardial Attenuation on Coronary Computed Tomography Angiography Predicts Postoperative Adverse Cardiovascular Events: Coronary CTA VISION Substudy.
Normalized Subendocardial Myocardial Attenuation on Coronary Computed Tomography Angiography Predicts Postoperative Adverse Cardiovascular Events: Coronary CTA VISION Substudy. Circ Cardiovasc Imaging. 2022 01; 15(1):e012654.
PMID: 35041449
Preoperative Assessment of Anxiety and Depression Using Computerized Adaptive Screening Tools: A Pilot Prospective Cohort Study.
Bass V, Brown F, Beiser DG, Peterson T, Gibbons RD, Nagele P. Preoperative Assessment of Anxiety and Depression Using Computerized Adaptive Screening Tools: A Pilot Prospective Cohort Study. Anesth Analg. 2021 Dec 24.
PMID: 34958316
Evaluation of Appropriate Use of Preoperative Echocardiography before Major Abdominal Surgery: A Retrospective Cohort Study.
Evaluation of Appropriate Use of Preoperative Echocardiography before Major Abdominal Surgery: A Retrospective Cohort Study. Anesthesiology. 2021 11 01; 135(5):854-863.
PMID: 34543408
NT-proBNP in young healthy adults undergoing non-cardiac surgery.
NT-proBNP in young healthy adults undergoing non-cardiac surgery. Clin Biochem. 2021 Oct; 96:38-42.
PMID: 34265286
A phase 2 trial of inhaled nitrous oxide for treatment-resistant major depression.
A phase 2 trial of inhaled nitrous oxide for treatment-resistant major depression. Sci Transl Med. 2021 06 09; 13(597).
PMID: 34108247
Austrian Cross of Honor for Science and Arts
Republic of Austria
2021
FAER Academy of Research Mentors in Anesthesiology (elected)
FAER
2019
Fellow
American Heart Association
2018
NARSAD Independent Investigator Grant
Brain & Behavior Research Foundation
2016
Ziskind-Somerfeld Research Award
Society for Biological Psychiatry
2016
Mentor of the Year
Clinical Research Training Center, Washington University School of Medicine
2014
Presidential Scholar Award
American Society of Anesthesiologists
2012
Billroth Prize
Vienna Medical Society (Austria)
2011
Elmer-Zsigmond Award
International Society for Anesthetic Pharmacology
2007
Otto-Kraupp-Prize
2006
Research Starter Grant
European Society of Anaesthesiology
2005
Resident’s Research Essay Contest Award
American Society for Anesthesiology
2005