Towards a potent and rapidly reversible Dexmedetomidine-based general anesthetic.
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Rapid emergence from dexmedetomidine sedation in Sprague Dawley rats by repurposing an a2-adrenergic receptor competitive antagonist in combination with caffeine.
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Caffeine reverses the unconsciousness produced by light anesthesia in the continued presence of isoflurane in rats.
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A pilot study showing that repeated exposure to stress produces alterations in subsequent responses to anesthetics in rats.
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Caffeine Accelerates Emergence from Isoflurane Anesthesia in Humans: A Randomized, Double-blind, Crossover Study.
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Caffeine accelerates recovery from general anesthesia via multiple pathways.
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Caffeine accelerates recovery from general anesthesia.
Caffeine accelerates recovery from general anesthesia. J Neurophysiol. 2014 Mar; 111(6):1331-40.
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Interaction of anesthetics with neurotransmitter release machinery proteins.
Interaction of anesthetics with neurotransmitter release machinery proteins. J Neurophysiol. 2013 Feb; 109(3):758-67.
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Three-in-one nerve block with different concentrations of bupivacaine in total knee arthroplasty: randomized, placebo-controlled, double-blind trial.
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Etomidate and propofol inhibit the neurotransmitter release machinery at different sites.
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